노화는 질병이다: ‘노화 치료의 시대’가 시작된다

 노화 의학 및 통합의학 분야의 권위자인 이영진 교수님 이 제시한 새로운 의료 패러다임, **‘노화 치료(Age-Treatment)’**에 대해 깊이 있게 살펴보겠습니다. 예전과 달리 이제 노화는 피할 수 없는 자연 현상이 아니라, **고혈압이나 당뇨처럼 조기에 진단하고 치료할 수 있는 ‘질병’**으로 바라봐야 한다는 관점이 빠르게 자리 잡고 있습니다. 1. 노화는 질병이다 (Geroscience 관점) 최근 연구들은 노화를 단순히 나이 듦이 아니라, **과학적으로 규명 가능한 ‘병적 과정’**으로 설명합니다. 세포에서는 다음과 같은 10여 가지 공통적인 노화 현상이 발견됩니다. DNA 손상 텔로미어 단축 미토콘드리아 기능 저하 노쇠(좀비) 세포 증가 세포 내 단백질 항상성 붕괴 등 이러한 ‘세포 노화 현상’을 조기에 파악하고 개입하면, 질병이 나타나기 전에 예방 할 수 있다는 것이 노화 의학의 핵심 메시지입니다. 2. 건강 수명 연장의 3단계: 노화 감속(Slowdown Aging) 인류는 지금까지 여러 방식으로 수명을 늘려 왔습니다. 그중 현재 가장 주목받는 단계가 바로 **노화 감속(Slowdown Aging)**입니다. ✔️ 노화 감속이 중요한 이유 노화 속도를 늦추면 각종 만성 질환 발생을 근본적으로 억제 세포 단위에서 발생하는 노화 지표를 미리 측정 질병이 생기기 전에 선제적 치료 가능 즉, “아프기 전에 치료하는 의료”가 본격적으로 열리고 있다는 의미입니다. 3. 미래의 노화 치료 기술 (4단계: 역노화 Reverse Aging) 미래의 의료혁신은 ‘노화를 되돌리는 것’에 초점이 맞춰질 것입니다. 부분적 역노화 (2030년대) 3개의 유전자만을 활용해 세포를 줄기세포로 돌아가지 않게 하면서 피부 근육 특정 장기 같은 원하는 부위만 선택적으로 젊게 만드는 기술 이 상용화될 전망입니다. 전신 역노화 (2050년대) 전신을 젊어지게 하는 유전자 재프로그래밍 기술이...

Encountering Cancer in the Maze

 Professor Kim Gyuwon, an expert in cancer, has written a book that chronicles his journey through battling cancer. Having suffered from the disease for a long time, he has lost his sense of smell, taste, and much of his hearing, and he has turned his experiences into a written account. Reading his book evokes a profound sense of goodwill from start to finish, and I am truly grateful for that.

The book consistently raises the question of why cancer attempts to thrive by breaking down its own foundation (the body). It details the progression from initial diagnosis to recurrence, multiple surgeries, and chemotherapy, revealing how he has personally endured the illness he has studied his entire life. He reflects on how chemotherapy leaves traces in the body and what it really means for those who are suffering from it. The book also presents a friendly overview of the history of cancer treatment over the past century, while posing the fundamental question of what life truly is in the search for breakthroughs and limitations in treatment.


While traditional chemotherapy shows definitive effects, it also comes with terrifying side effects. This has led humanity to delve into understanding the body and cells, even reaching the realm of genomics. However, he notes that we have encountered a dilemma where we can’t go further in understanding cells. The fact that cancer treatment has become trapped within cellular issues underscores that cancer is fundamentally a problem of organs, which he argues is often overlooked. He emphasizes that the interactions between cells, as well as their connections beyond their immediate neighbors, are as crucial as the internal cellular issues.


This concept aligns with the work of American psychologist Ken Wilber, who explains the dimensions of atoms, cells, and the entire human body as holons. While we acknowledge that humans are made of cells, we are also so much more than that. Phenomena that do not exist at the cellular level can manifest at the organ level, and human beings can perform functions that are unimaginable to individual organs.


In his book, Professor Kim describes cancer as a phenomenon where certain parts of a multicellular body attempt to revert to a unicellular state. This is akin to how, despite living in a society, each individual inherently possesses a solitary nature. He draws a parallel between this intrinsic aspect and the reasons behind the proliferation of cancer within the social body.

I extend my gratitude and respect to Professor Kim for showcasing profound insights about cancer and life in this small book. Furthermore, I sincerely wish for him to break free from the struggles of cancer and complete his reflections. This is also a light and hope for all of us.


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